About Variome

Variome is an independent educational resource created to explain scientific evidence regarding inter-individual variability in responses to dietary interventions. The site exists solely to provide accessible information about how and why people respond differently to the same dietary approaches.

We are not a commercial service, a diet provider, a testing platform, or a personalisation engine. We do not sell products, services, or personalised diet plans. We do not offer genetic or microbiome testing. We do not promise weight loss outcomes or health transformations.

Variome documents what nutritional science has documented: that standardised dietary approaches produce highly variable individual outcomes, and this variability is a natural feature of human biology.

Variome explores the scientific evidence for dietary response heterogeneity through articles on:

• Genetic and epigenetic contributions to dietary response variability
• Gut microbiome composition and its influence on individual outcomes
• Behavioural and psychological factors affecting adherence and response
• Landmark randomised controlled trials showing wide standard deviations in results
• How population-level guidelines reflect and account for individual differences
• Current limitations in predicting individual dietary response from biological markers
• The interaction of diet with broader lifestyle context (activity, sleep, stress)
• Observational evidence from large cohort studies showing diverse trajectories

We do not:

• Promise that any diet is superior for weight loss or health outcomes
• Suggest that personalisation guarantees better results than standardised approaches
• Offer or promote DNA, microbiome, or genetic testing for dietary optimisation
• Provide personalised diet plans, meal templates, or individualised frameworks
• Publish weight loss success stories or before-and-after testimonials
• Advocate for any particular dietary philosophy or approach over others
• Sell products, supplements, tests, or professional services
• Provide medical or personal dietary advice

We aim to explain, not persuade. To inform, not advise. To document scientific evidence, not to influence individual choices.

We present variability as a feature of human biology worthy of understanding and respect—not as a problem to be solved through testing, personalisation, or proprietary solutions.

All content reflects available peer-reviewed evidence and public health communications from organisations such as the UK National Health Service, the Eatwell Guide, and major nutritional research reviews. We do not promote novel frameworks or untested approaches.

All content on Variome is written in accessible language but grounded in scientific evidence. References are drawn from controlled trials, cohort studies, meta-analyses, and guidelines published by recognised public health and scientific bodies.

The site prioritises accuracy and intellectual honesty. Where evidence is limited, contested, or evolving, we indicate this. We do not present speculative ideas as established fact, nor do we overstate the implications of research findings.

The information on Variome describes general scientific principles and patterns. It does not account for individual circumstances, medical conditions, medications, or personal history.

If you have specific health concerns, dietary restrictions, or are taking medications, please consult your healthcare provider or a qualified registered dietitian before making significant dietary changes.

For questions, feedback, or inquiries about Variome, you may reach us via our contact page.